Engineering the Therapeutics of the Future

Co-Located with Molecular Med TRI-CON Asia

May 28-31, 2013
Marina Bay Sands, Singapore

Co-Located Bio-IT World Asia

 

This track will showcase novel research and collaborative initiatives leveraging Electronic Medical Record systems and e-Clinical Trial Management systems. Panel discussions on practical issues in managing clinical trials in Asia will feature representatives from the pharmaceutical, CRO and data analytics perspectives.

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Wednesday, May 29

8:00 Registration & Morning Coffee


BIG DATA, BIG MEDICINE  

8:30 Chairperson’s Remarks

Narendra K. Saini, CEO, Sukrut Systems

8:40 Doctors- Patients, the Highway Communication

Jayadeep ReddyJayadeep Reddy , Founder and C.E.O, e Health Access Pvt Ltd

In today’s world, we are bombarded by the Internet and mobile technologies. The technology that is constantly changing is influencing the way Doctors and Patients communicate. The communication has changed paramount via audio, video, chat, e-mail etc.

This paper talks about how the latest modes of communication impact our daily lives with respect to healthcare. It gives doctors an opportunity to serve society in a better manner by not restricting to clinic alone, thereby reaching more patients; also doctors are able to spend quality time with patients. With the different modes of communication, patient is in a better position to interact with specialists. They have an easy, anytime, anywhere access to expert advice expediently. In particular, it is helpful for aged patients who with a little knowledge on technology can interact with Doctors effectively without having to depend.

9:00 Mobile and Cloud - Rethinking Diagnostics

Sailesh ChutaniSailesh Chutani, Ph.D., President and CEO, Mobisante, Inc.

Point-of-care diagnostics devices coupled with the power of real-time data in the cloud, can revolutionize access to health care while reducing costs. Such devices can be made simple enough and affordable to be used by mid-level professionals in the field. Connectivity allows access to remote experts, storage of data in the cloud, as well as intensive computations and analysis of that data. Mobisante has used this model to create a smart phone and cloud-based ultrasound imaging system, where the collected set of images can be archived in the cloud, processed for enhancements, and analyzed for providing guidance.

PerkinElmer NEW 20099:20 Case Studies in How to Extract the Value of Scientific Data

Clive Higgins, Vice President, Marketing, Informatics, PerkinElmer

9:50 Coffee Break in the Exhibit Hall with Poster Viewing

10:40 M2M Perspective of the New World Health Paradigm

Narendra SainiNarendra Saini, CEO, Sukrut Systems

M2M is chipping in every part of life, and health segment is not untouched by it either. There have been tremendous efforts in the recent times by the M2M community to not only contribute in the development, but also in efficient delivery of health services in general. This talk will revolve around the M2M technology that is being developed for a better health service delivery by way of service delivery platforms and a few use case scenario.

11:00 The Collaboration Imperative in Clinical Research

Gerard WongGerard Wong, Ph.D., Deputy Director, Investigational Medicine Unit (IMU), National University Health System, Singapore

In the search for better therapeutics and improved disease management, clinical research remains the vital element in bringing new products to market and translating new discoveries, technologies and procedures to actual medical practice. The complexities involved now warrant better and more effective ways to make a real clinical impact that decreases morbidity and mortality. To meet increasing demands from stakeholders and rising costs of healthcare, there is a new imperative for more collaboration.

EMC11:20 7 Billion Small Data Bins: A Systems View from Biology to Storage to Analytics

Sanjay Joshi, CTO, EMC Isilon Storage Division

There is a global effort underway to understand the complexity of humans and their health and apply it to clinical practice. This endeavor requires systems thinking at massive scale. We will present a practical approach based on the combined analysis of our customers who are beginning to knock on the doors of Exa-Scale data.

11:50 Panel Discussion: Healthcare Ecosystem Going through a Paradigm Shift

Moderator:
Stanley Y. Shaw, M.D., Ph.D., Co-Director, Center for Assessment Technology and Continuous Health (CATCH), Massachusetts General Hospital (MGH); Co-Director of Chemical Biology, MGH Center for Systems Biology; Assistant Professor, Harvard Medical School
Panelists:
Jayadeep Reddy, Co-Founder and CEO, e Health Access Pvt Ltd

Narendra Saini, Sukrut Systems

Samik Ghosh, Ph.D., Senior Research Scientist, Systems Biology Institute

12:30 Lunch on Your Own


PRECISION PATIENT RECRUITMENT  

13:40 Chairperson’s Remarks

Samik Ghosh, Ph.D., Senior Research Scientist, Systems Biology Institute

13:50 Systems Biology Approaches for Targeted and Combination Therapeutics

Samik GhoshSamik Ghosh, Ph.D., Senior Research Scientist, The Systems Biology Institute, Tokyo

The increasing availability of omics-scale data across multiple spatio-temporal levels provides unique challenges and opportunities in the application of computational tools and techniques to obtain insights from big data biology. Particularly, systems level approaches are playing an increasing important role in drug discovery and translational medicine research. In this talk, we share our experiences in application of systems biology approaches for targeted therapeutics in oncology with a key focus on cohort stratification, indication differentiation and combination partner selection.

14:10 Ultrasensitive RNA In Situ Hybridization for Tissue Diagnostics

Yuling LuoYuling Luo, Ph.D., Founder, President & CEO, Advanced Cell Diagnostics, Inc.

RNA biomarkers are traditionally analyzed by “grind-and-bind” assays such as RT-PCR, which loses critical cellular and tissue context for clinical interpretation. Recent advances in in situ RNA analysis capable of detecting single RNA molecules in routine clinical specimens may finally enable more advanced RNA-based tissue diagnostics

 

14:30 Patient Segmentation and Combination Approaches in Oncology Clinical Development

Carl Firth, Ph.D., MBA, Chief Executive Officer, ASLAN Pharmaceuticals Pte. Ltd.

It is becoming increasingly apparent that the future success in finding effective treatments for cancer patients will depend on identifying the patients that will respond to a given class of drugs. Given the inherent complexity and redundancy in these pathways, it is also likely many patients will require combinations of targeted agents. Though the theory is clear, implementing these paradigms in clinical development and in the market is challenging, and will require scientists, clinicians, drug developers and payors to work together to transform the way in which we approach the disease.

14:50 Q&A with Session Speakers

15:00 Refreshment Break in the Exhibit Hall with Poster Viewing


» KEYNOTE SESSION  

16:00 Chairperson’s Remarks

Marcel Dinger, Ph.D., Associate Professor, Head of Genome Informatics, Garvan Institute for Medical Research, The Kinghorn Cancer Center

16:10 Sequencing the Faroe Islands – From Sequencing to Societal Implementation and Personalized Health

Bogi EliasenBogi Eliasen, Program Director, FarGen, Ministry of Health, Faroe Islands

The FarGen project proposes to implement routine whole genome sequencing in healthcare for a whole society of 50,000 people, the Faroe Islands. The vision is to provide a cornerstone for optimal individualized healthcare with emphasis on prevention as well as treatment, cost effectiveness and democratic implementation on the road to personalized health with empowered citizens. It is also to provide a foundation and resource for national and international research and to develop a genomic healthcare model that has national and global compatibility and be a part of the development of precision medicine and personalized health.

16:40 Implementing Clinical and Research Trio Whole Genome and Exome Sequencing for Diagnosis of Rare Diseases

Jimmy LinJimmy Lin, M.D., Ph.D., MHS, Founder and President, Rare Genomics Institute; Research Instructor, Washington University St. Louis

Developments in DNA sequencing technology have provided a unique opportunity for diagnosis and discovery of genetic alterations for rare diseases. Partnering with 20 academic centers in the US and globally, we have coordinated and facilitated NGS projects for rare disease. We will summarize what we learned from all these sites for the entire process from consent, sample collection, library prep, sequencing, bioinformatics, interpretation, counseling, and clinical reimbursement.


17:10 Panel Discussion: Genomics-Driven Precision Medicine

Moderator:

Nandita Mullapudi, Ph.D., Principal Scientist & Group Leader - Next Gen Sequencing Lab, Genotypic Technology Pvt Ltd

Panelists:
Bogi Eliasen, Program Director, FarGen, Ministry of Health, Faroe Islands

Jimmy Lin, M.D., Ph.D., MHS, Founder and President, Rare Genomics Institute; Research Instructor, Washington University St. Louis

Piero Carninci, Ph.D., Director, Division of Genomics Technologies, RIKEN Center for Life Science Technologies

Marcel Dinger, Ph.D., Associate Professor, Head of Genome Informatics, Garvan Institute for Medical Research, The Kinghorn Cancer Center


17:30 Dinner Short Course Registration

18:00 – 20:00 Dinner Short Courses (Separate Registration Required)



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